Evidence / Sources / E230
Coburn SL, Crossley KM, Kemp JL, Warden SJ, West TJ, Bruder AM, Mentiplay BF, Culvenor AG. Immediate and delayed effects of joint loading activities on knee and hip cartilage: a systematic review and meta-analysis. Sports Med Open 2023;9(1):56. The closest thing to a mechanobiology-informed loading dose; its pooled studies are observational repeated-measures rather than trials. Full text held
▲Systematic review and meta-analysis · n = 40 studies, 653 participants · Immediate to 48 hours follow-upHEALTHY AND OSTEOARTHRITIC ADULTS, KNEEFull text →
Everything on this site that leans on E230 — 0 claims
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Population
Healthy and osteoarthritic adults, knee — a different population from MACI itself. Wherever this source appears, that flag appears with it.
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