Urgent warning signs — calf pain or swelling, fever, the knee locking — are one tap away, always.Something feel wrong?Red flags →
AFTER MACI
Evidence / Sources / E273

Husted RS, Troelsen A, Husted H, Grønfeldt BM, Thorborg K, Kallemose T, Rathleff MS, Bandholm T. Knee-extensor strength, symptoms, and need for surgery after two, four, or six exercise sessions per week (the QUADX-1 trial). Held as the open medRxiv preprint of Osteoarthritis Cartilage 2022;30(7):973-986. Randomised exercise frequency directly and found no dose-response. Full text held

▲RCT, three arms, dose-response · n = 140 · 12 months follow-upEND-STAGE KNEE OA, PRE-ARTHROPLASTYDOI / full text →
Everything on this site that leans on E273 — 0 claims

Nothing cites this source yet — it is part of the vetted evidence base for content still being written.

Population
End-stage knee OA, pre-arthroplasty — a different population from MACI itself. Wherever this source appears, that flag appears with it.
Selection policy
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