Urgent warning signs — calf pain or swelling, fever, the knee locking — are one tap away, always.Something feel wrong?Red flags →
AFTER MACI
Evidence / Sources / E41

Guillén-García P et al. Increasing the Dose of Autologous Chondrocytes Improves Articular Cartilage Repair: Histological and Molecular Study in the Sheep Animal Model. Cartilage 2014

▲Controlled laboratory (sheep) · n = 15 sheep (3 arms of 5)ANIMAL (SHEEP), FEMORAL CONDYLEFull text →
Everything on this site that leans on E41 — 2 claims
What we don't know · № 23“No trial has compared the high-density technique against standard MACI in people, in either direction.”HD-ACI (ICC) · two names, one operation“The density the technique is named for rests on one animal study: in a sheep model, five million chondrocytes per cm² produced hyaline-like cartilage that varied less and resembled…”
Population
Animal (sheep), femoral condyle — a different population from MACI itself. Wherever this source appears, that flag appears with it.
Selection policy
Sources enter the registry through docs/research — the evidence table records design, population, and size for every entry, and pages cannot cite anything outside it.