Urgent warning signs — calf pain or swelling, fever, the knee locking — are one tap away, always.Something feel wrong?Red flags →
AFTER MACI
Evidence / Sources / E44

Guillén-Vicente I et al. Intermediate-Term Clinical Outcomes of High-Density Autologous Chondrocyte Implantation in Patients with Concomitant Anterior Cruciate Ligament Reconstruction and Focal Chondral Lesions. Cartilage 2025

Evidence strength 2 of 5
Comparative case series · n = 48 (24 ACLR / 24 intact) · 2 yr follow-upMACI ITSELFFull text →
Everything on this site that leans on E44 — 1 claim
HD-ACI (ICC) · what the human results show“In forty-eight knees compared with and without a concurrent ACL reconstruction, both groups improved past the threshold that counts as a meaningful change, with no significant diff…”
Population
HD-ACI, knee
Selection policy
Sources enter the registry through docs/research — the evidence table records design, population, and size for every entry, and pages cannot cite anything outside it.