Urgent warning signs — calf pain or swelling, fever, the knee locking — are one tap away, always.Something feel wrong?Red flags →
AFTER MACI
Evidence / Sources / E8

Brittberg M et al. …Five-Year Follow-up (SUMMIT Extension). AJSM 2018

Evidence strength 4 of 5
RCT extension · n = 128 · 5 yr follow-upMACI ITSELFFull text →
Everything on this site that leans on E8 — 1 claim
Benchmarks · KOOS Pain“37.0 → 82.5 at 2 years — SUMMIT randomized trial, MACI arm, defects ≥3 cm²”
Population
Defects ≥3 cm², condyle/trochlea (SUMMIT cohort)
Selection policy
Sources enter the registry through docs/research — the evidence table records design, population, and size for every entry, and pages cannot cite anything outside it.